Abstract
Protamine hydrochloride adsorbed onto citrated superparamagnetic iron oxide nanoparticles represents an efficient tool for capturing and concentration of hepatitis-C virus from plasma samples, improving the sensitivity of downstream analysis by nucleic acid testing.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adsorption
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Dextrans / chemistry
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Hepacivirus / chemistry*
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Hepacivirus / genetics
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Hepacivirus / isolation & purification
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Humans
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Magnetite Nanoparticles / chemistry*
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Protamines / chemistry*
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RNA, Viral / analysis
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Reverse Transcriptase Polymerase Chain Reaction
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Thrombin / chemistry
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Thrombin / metabolism
Substances
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Dextrans
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Magnetite Nanoparticles
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Protamines
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RNA, Viral
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Thrombin
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ferumoxides