Patient-reported health data are critical components of patient-centered health care. However, barriers related to acquisition, implementation, and data use have not been well characterized. We conducted a systematic review of literature about health assessments in ambulatory and primary care covering 2 domains: (1) best practices in health assessments in primary care and (2) integration of health assessments into electronic health records. Our review found that training and standardization of practice workflows improves implementation of health assessments; however, gaps remain on identification and selection of health assessments, integration with electronic health records, and optimal intervals of health assessments administration.