Successful treatment using high-dose intravenous immunoglobulin in a patient with rapidly progressive interstitial pneumonia associated with dermatomyositis

Y Nagatomo; A Okayama; K Murai; T Sasaki; M Kuroki; G Tanaka; M Iga; Y Kai; H Tsubouchi

doi:10.3109/s101650070025

Successful treatment using high-dose intravenous immunoglobulin in a patient with rapidly progressive interstitial pneumonia associated with dermatomyositis

Mod Rheumatol. 2000 Sep;10(3):165-8. doi: 10.3109/s101650070025.

Authors

Y Nagatomo¹, A Okayama, K Murai, T Sasaki, M Kuroki, G Tanaka, M Iga, Y Kai, H Tsubouchi

Affiliation

¹ Department of Internal Medicine II, Miyazaki Medical College , 5200 Kihara, Kiyotake, Miyazaki 889-1601 , Japan.

PMID: 24383595
DOI: 10.3109/s101650070025

Abstract

Abstract A 36-year-old male patient with dermatomyo-sitis (DM) associated with rapidly progressive interstitial pneumonia (IP) was successfully treated by high-dose intravenous immunoglobulin (IVIG). He suffered from myopathy, skin lesions, and IP. In spite of the treatment with a high-dose corticosteroid, IP progressed rapidly. Then high-dose intravenous immunoglobulin (20 g/day, 4 days) was administered. The skin lesions, myopathy, and pulmonary lesions improved. High-dose IVIG was considered to be a relatively safe and effective treatment for progressive IP associated with DM.