Cardiac stem cell biology: glimpse of the past, present, and future

Circ Res. 2014 Jan 3;114(1):21-7. doi: 10.1161/CIRCRESAHA.113.302895.

Abstract

Cardiac regeneration strategies and de novo generation of cardiomyocytes have long been significant areas of research interest in cardiovascular medicine. In this review, we outline a variety of common cell sources and methods used to regenerate cardiomyocytes and highlight the important role that key Circulation Research articles have played in this flourishing field.

Keywords: adult stem cells; embryonic stem cells; induced pluripotent stem cells.

Publication types

  • Historical Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Differentiation
  • Heart / physiology*
  • Heart Diseases / surgery
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Myocytes, Cardiac / cytology*
  • Regeneration*
  • Stem Cell Research / history
  • Stem Cell Transplantation* / history
  • Stem Cell Transplantation* / trends
  • Stem Cells / classification
  • Stem Cells / cytology