Iatrogenic colorectal Kaposi sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient

Lamine Hamzaoui; Houda Kilani; Mahdi Bouassida; Moufida Mahmoudi; Emna Chalbi; Karima Siai; Heykel Ezzine; Hassen Touinsi; Mohamed M'saddak Azzouz; Sadok Sassi

doi:10.11604/pamj.2013.15.154.2988

Iatrogenic colorectal Kaposi sarcoma complicating a refractory ulcerative colitis in a human immunodeficiency negative-virus patient

Pan Afr Med J. 2013 Aug 29:15:154. doi: 10.11604/pamj.2013.15.154.2988. eCollection 2013.

Affiliations

¹ Gastroenterology department, Mohamed Tahar Maamouri Hospital, Nabeul, Tunisia.
² Histopathology department, Mohamed Tahar Maamouri Hospital, Nabeul, Tunisia.
³ General surgery department, Mohamed Tahar Maamouri Hospital, Nabeul, Tunisia.

Abstract

Kaposi sarcoma is a mesenchymal tumor associated to a human herpes virus-8. It often occurs in human immunodeficiency virus-positive subjects. Colorectal localization is rare. We report the case of a colorectal Kaposi sarcoma complicating a refractory ulcerative colitis treated with surgery after the failure of immunomodulator therapy in a human immunodeficiency virus-negative heterosexual man.

Keywords: Human Herpes Virus-8; Infliximab; Kaposi's Sarcoma; immunosuppression; ulcerative colitis.

Publication types

Case Reports

MeSH terms

Adult
Antibodies, Monoclonal / administration & dosage
Azathioprine / administration & dosage
Colitis, Ulcerative / complications*
Colitis, Ulcerative / drug therapy
Colitis, Ulcerative / surgery
Colorectal Neoplasms / complications*
Colorectal Neoplasms / diagnosis
Colorectal Neoplasms / surgery
HIV Seronegativity
Humans
Iatrogenic Disease
Infliximab
Male
Sarcoma, Kaposi / complications*
Sarcoma, Kaposi / diagnosis
Sarcoma, Kaposi / surgery
Steroids / administration & dosage
Treatment Failure

Substances

Antibodies, Monoclonal
Steroids
Infliximab
Azathioprine