Language outcomes following neurosurgery for brain tumours: a systematic review

NeuroRehabilitation. 2014;34(3):499-514. doi: 10.3233/NRE-141053.

Abstract

Background: Language function is susceptible to the effects of brain tumours during both the tumour growth phase and during neurosurgical resection.

Aim: This paper aimed to systematically review existing literature to determine the current status of knowledge about language outcomes following neurosurgery.

Methods: A systematic review was conducted involving a detailed literature search using online databases, quality assessment of relevant articles and data extraction.

Results: Of the 1449 articles retrieved, nine articles satisfied the study criteria. Overall, these studies reported variable patterns of language function post-surgery, however, there was a trend towards an early post-surgical decline in language function that greatly improved by 3 months. The likelihood of developing post-surgical communication impairments was influenced by a number of factors including pre-operative aphasia and the identification of sub-cortical language tracts inside the tumour margin, however, further research is required to fully elucidate pertinent predictors.

Conclusion: These findings have implications for rehabilitation programs following brain tumour surgery and suggest that there are a number of key gaps warranting further investigation.

Keywords: Brain tumour; aphasia; language; language impairment; neurosurgery; systematic review.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Aphasia / etiology
  • Brain Neoplasms / surgery*
  • Humans
  • Language
  • Language Disorders / etiology*
  • Postoperative Complications*