Coat's-like exudation in rhodopsin retinitis pigmentosa: successful treatment with an intravitreal dexamethasone implant

Eye (Lond). 2014 Apr;28(4):449-51. doi: 10.1038/eye.2013.314. Epub 2014 Jan 24.

Abstract

Purpose: Role of intravitreal injection of dexamethasone implant (Ozurdex) for refractory macular thickening.

Methods: A case report of a 13-year-old boy with Rhodopsin-positive, CRB1-negative retinitis pigmentosa presenting with Coat's-like exudative vitreoretinopathy and treatment-resistant cystoid macular oedema.

Results: A reduction in the macular thickening following a single injection of Ozurdex.

Conclusion: We present our experience in successful treatment of refractory macular oedema with intravitreal injection of dexamethasone implant resulting in clinically significant resolution of macular thickening.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Inflammatory Agents / administration & dosage*
  • Dexamethasone / administration & dosage*
  • Drug Implants
  • Exudates and Transudates
  • Humans
  • Intravitreal Injections
  • Macular Edema / drug therapy*
  • Male
  • Retinitis Pigmentosa / complications*
  • Rhodopsin / metabolism*
  • Treatment Outcome
  • Vitreoretinopathy, Proliferative / drug therapy*

Substances

  • Anti-Inflammatory Agents
  • Drug Implants
  • Dexamethasone
  • Rhodopsin