Cisplatin-induced gastric paresis

J Neurooncol. 1987;5(3):237-40. doi: 10.1007/BF00151227.

Abstract

A 27 year old male with metastatic testicular carcinoma was treated with cisplatin, vinblastine, and bleomycin (PVB) chemotherapy. After receiving a cumulative dose of 500 mg/m2 of cisplatin, he developed severe nausea and vomiting and had clinical evidence of a cisplatin-induced peripheral neuropathy. His vomiting resolved five weeks after discontinuation of cisplatin. We believe this case represents the first report of gastric autonomic neuropathy induced by cisplatin.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols*
  • Bleomycin / therapeutic use
  • Cisplatin / adverse effects*
  • Cisplatin / therapeutic use
  • Humans
  • Male
  • Peripheral Nervous System Diseases / chemically induced*
  • Stomach / innervation*
  • Stomach Diseases / chemically induced*
  • Testicular Neoplasms / drug therapy*
  • Testicular Neoplasms / secondary
  • Vinblastine / therapeutic use

Substances

  • Bleomycin
  • Vinblastine
  • Cisplatin

Supplementary concepts

  • PVB protocol