[Hypertension secondary to treatment with latanoprost]

Abstract

Case report: An 80 year old woman operated on by trabeculectomy for primary open-angle glaucoma due to increased pressure, who started treatment with latanoprost. Monitoring of blood pressure (BP) showed a statistically significant increase in both systolic and diastolic BP, coinciding with the use of topical hypotensive, which resolved by voluntarily suspending treatment, thus increasing again to reintroduce the prostaglandin.

Discussion: Prostaglandin analogs reduce intraocular pressure to produce vasodilation of the episcleral and ciliary arteries, increasing the outflow of aqueous humor. Cardiovascular effects are rare, but have been described by the vasoconstrictor effect that can trigger the reversible increase in BP, as in this case.

Keywords: Glaucoma; Hipertensión arterial; Hipertensión ocular; Hypertension; Latanoprost; Ocular hypertension, Glaucoma; Vasoconstricción; Vasoconstriction.