Underdosing of prophylactic valganciclovir due to inaccurate estimation of glomerular filtration rate leading to severe cytomegalovirus disease in a kidney transplant recipient

Antimicrob Agents Chemother. 2014;58(2):1271-2. doi: 10.1128/AAC.01816-13.

Authors

E L Penne¹, S A Nurmohamed

Affiliation

¹ Department of Nephrology, VU University Medical Center, Amsterdam, the Netherlands.

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Acute Disease
Adult
Antiviral Agents / therapeutic use*
Cytomegalovirus / pathogenicity
Cytomegalovirus / physiology
Cytomegalovirus Infections / drug therapy*
Cytomegalovirus Infections / immunology
Cytomegalovirus Infections / pathology
Cytomegalovirus Infections / virology
Drug Dosage Calculations
Drug Monitoring
Ganciclovir / analogs & derivatives*
Ganciclovir / therapeutic use
Glomerular Filtration Rate
Humans
Immunosuppression Therapy
Kidney / drug effects
Kidney / immunology
Kidney / pathology
Kidney / virology
Kidney Transplantation*
Male
Medication Errors*
Valganciclovir
Viral Load / drug effects

Substances

Antiviral Agents
Valganciclovir
Ganciclovir