An expanding world of small RNAs

Zachary T Neeb; Alan M Zahler

doi:10.1016/j.devcel.2014.01.009

An expanding world of small RNAs

Dev Cell. 2014 Jan 27;28(2):111-2. doi: 10.1016/j.devcel.2014.01.009.

Authors

Zachary T Neeb¹, Alan M Zahler²

Affiliations

¹ Department of Molecular, Cell and Developmental Biology and The Center for Molecular Biology of RNA, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
² Department of Molecular, Cell and Developmental Biology and The Center for Molecular Biology of RNA, University of California, Santa Cruz, Santa Cruz, CA 95064, USA. Electronic address: zahler@ucsc.edu.

Abstract

In ciliated protozoans, small RNAs (sRNAs) are integral to guiding large-scale genomic rearrangements after mating. Sandoval et al. (2014) report in this issue of Developmental Cell the discovery of a class of Paramecium sRNAs, produced by a unique Dicer-like enzyme, that likely provides late stage quality control in this process.

Publication types

Comment

MeSH terms

Genome, Protozoan*
Paramecium tetraurelia / genetics*
RNA, Protozoan / genetics*
RNA, Small Untranslated / genetics*
Ribonuclease III / genetics*

Substances

RNA, Protozoan
RNA, Small Untranslated
Ribonuclease III

Grants and funding

T32 GM008646/GM/NIGMS NIH HHS/United States