Wound bed preparation 2014 update: management of critical colonization with a gentian violet and methylene blue absorbent antibacterial dressing and elevated levels of matrix metalloproteases with an ovine collagen extracellular matrix dressing

Adv Skin Wound Care. 2014 Mar;27(3 Suppl 1):1-6. doi: 10.1097/01.ASW.0000443269.63406.f9.

Abstract

Wound bed preparation (WBP) is a paradigm for holistic patient care that includes treatment of the cause along with patient-centered concerns before optimizing the components of local wound care (debridement, infection/inflammation, moisture balance, and, when required, the edge effect). This review incorporates a methylene blue and gentian violet bound foam dressing for critical colonization and an ovine collagen extracellular matrix dressing for reduction of elevated levels of matrix metalloproteases into the WBP paradigm.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use*
  • Biological Dressings*
  • Colony Count, Microbial
  • Combined Modality Therapy
  • Debridement / methods
  • Extracellular Matrix / drug effects
  • Extracellular Matrix / physiology
  • Female
  • Gentian Violet / pharmacology
  • Humans
  • Male
  • Metalloproteases / metabolism*
  • Methylene Blue / pharmacology
  • Occlusive Dressings
  • Patient-Centered Care / methods
  • Risk Assessment
  • Severity of Illness Index
  • Sheep
  • Surgical Wound Infection / prevention & control
  • Treatment Outcome
  • Wound Healing / physiology*
  • Wounds and Injuries / diagnosis
  • Wounds and Injuries / therapy*

Substances

  • Anti-Bacterial Agents
  • Metalloproteases
  • Gentian Violet
  • Methylene Blue