Synergistic activity and effectiveness of a double-carbapenem regimen in pandrug-resistant Klebsiella pneumoniae bloodstream infections

J Antimicrob Chemother. 2014 Jun;69(6):1718-20. doi: 10.1093/jac/dku027. Epub 2014 Feb 11.

Authors

Alessandra Oliva¹, Alessandra D'Abramo¹, Claudia D'Agostino¹, Marco Iannetta¹, Maria T Mascellino¹, Carmela Gallinelli¹, Claudio M Mastroianni², Vincenzo Vullo¹

Affiliations

¹ Dipartimento di Sanità Pubblica e Malattie Infettive, Sapienza Università, Piazzale Aldo Moro, 00185 Rome, Italy.
² Dipartimento di Sanità Pubblica e Malattie Infettive, Sapienza Università, Piazzale Aldo Moro, 00185 Rome, Italy UOC Malattie Infettive, Fondazione Eleonora Lorillard Spencer Cenci, Sapienza Università, Corso della Repubblica, 04100 Latina, Italy claudio.mastroianni@uniroma1.it.

PMID: 24521856
DOI: 10.1093/jac/dku027

No abstract available

Keywords: KPC; bacteraemia; ertapenem; meropenem; nosocomial infections.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Bacteremia / drug therapy*
Bacteremia / microbiology
Carbapenems / pharmacology*
Carbapenems / therapeutic use*
Drug Resistance, Multiple, Bacterial*
Drug Synergism
Drug Therapy, Combination
Fatal Outcome
Humans
Klebsiella Infections / diagnosis
Klebsiella Infections / drug therapy*
Klebsiella Infections / microbiology
Klebsiella pneumoniae / drug effects*
Male
Microbial Sensitivity Tests
Treatment Outcome

Substances

Carbapenems