Antithymocyte globulin induced recurrent seizures in a case of severe aplastic anemia

Sanjeev Kumar Sharma; Pawan Kumar Singh; Tulika Seth; Pravas Mishra; Manoranjan Mahapatra

doi:10.1007/s12288-012-0183-6

Antithymocyte globulin induced recurrent seizures in a case of severe aplastic anemia

Indian J Hematol Blood Transfus. 2014 Mar;30(1):70-1. doi: 10.1007/s12288-012-0183-6. Epub 2012 Aug 21.

Authors

Sanjeev Kumar Sharma¹, Pawan Kumar Singh¹, Tulika Seth¹, Pravas Mishra¹, Manoranjan Mahapatra¹

Affiliation

¹ Department of Hematology, All India Institute of Medical Sciences, New Delhi, 110029 India.

Abstract

Antithymocyte globulin (ATG) has been the standard immuno suppressive therapy for aplastic anemia. ATG significantly improves survival and response rates vary between 40 and 70 %. Mild side effects are common but recurrent seizures have rarely been reported with ATG.

Keywords: Antithymocyte globulin; Aplastic anemia; Seizures.