Immunotherapeutic implications of the immunophenotype of pediatric brain tumors

Oncoimmunology. 2014 Jan 1;3(1):e27256. doi: 10.4161/onci.27256.

Abstract

The cytofluorometric analysis of dissociated tumor samples identified distinct immunophenotypes among the most common variants of pediatric brain tumor. These findings suggest that immunotherapeutic regimens against pediatric brain malignancies should be tailored to individual tumor types.

Keywords: flow cytometry; immune cell characterization; immunotherapy; pediatric brain tumor.