[Chemotherapy and partial surgery in epithelioma of the pharyngo-larynx]

Ann Otolaryngol Chir Cervicofac. 1988;105(6):409-14.
[Article in French]

Abstract

On the basis of a series of 185 patients, the authors evaluate the results of the therapeutic sequence chemotherapy-partial surgery in carcinomas of the pharyngolarynx. The action of chemotherapy is confirmed (80% clinical responses greater than 50%, 55% residual tumours or in complete histological regression). The therapeutic sequence chemotherapy-surgery gave 25% local failures and 1% lymph node failures. The development of the therapeutic strategy in carcinomas of the pharyngolarynx is considered in relation to the action of current modalities of chemotherapy.

Publication types

  • English Abstract

MeSH terms

  • Actuarial Analysis
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bleomycin / administration & dosage
  • Carcinoma / therapy*
  • Cisplatin / administration & dosage
  • Combined Modality Therapy
  • Fluorouracil / administration & dosage
  • Humans
  • Laryngeal Neoplasms / therapy*
  • Lymphatic Metastasis
  • Methotrexate / administration & dosage
  • Pharyngeal Neoplasms / therapy*

Substances

  • Bleomycin
  • Cisplatin
  • Fluorouracil
  • Methotrexate