Frictional purpuric eruption associated with angiotensin II receptor blockers

Dermatol Ther. 2014 Mar-Apr;27(2):97-100. doi: 10.1111/dth.12063. Epub 2013 May 21.

Abstract

Angiotensin II receptor blockers (ARBs) are drugs generally well tolerated. There are few reports about cutaneous side effects of ARBs. The present authors describe herein four cases of purpuric eruption mainly involving sites of friction in patients taking ARBs. These eruptions completely cleared after stopping the drug and implementing preservative measures to reduce friction.

Keywords: angiotensin II receptor blockers; cutaneous side effects; purpuric dermatitis.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Angiotensin II Type 1 Receptor Blockers / adverse effects*
  • Antihypertensive Agents / adverse effects*
  • Drug Eruptions / diagnosis
  • Drug Eruptions / etiology*
  • Drug Eruptions / therapy
  • Drug Substitution
  • Exanthema / chemically induced*
  • Exanthema / diagnosis
  • Exanthema / therapy
  • Female
  • Friction
  • Humans
  • Hypertension / drug therapy*
  • Male
  • Middle Aged

Substances

  • Angiotensin II Type 1 Receptor Blockers
  • Antihypertensive Agents