DNA fingerprinting: a quality control case study for human biospecimen authentication

Biopreserv Biobank. 2014 Apr;12(2):151-3. doi: 10.1089/bio.2013.0063. Epub 2014 Feb 14.

Abstract

This case study illustrates the usefulness of the DNA fingerprinting method in biobank quality control (QC) procedures and emphasizes the need for detailed and accurate record keeping during processing of biological samples. It also underlines the value of independent third-party assessment to identify points at which errors are most likely to have occurred when unexpected results are obtained from biospecimens.

MeSH terms

  • Biological Specimen Banks / standards*
  • Case-Control Studies
  • DNA / analysis
  • DNA / isolation & purification
  • DNA Fingerprinting*
  • Electrophoresis, Agar Gel
  • Humans
  • Quality Control

Substances

  • DNA