Abstract
A 67-year-old woman had a basal cell carcinoma of the forehead containing numerous hyaline cytoplasmic inclusions. Electron microscopic studies revealed that these inclusions were aggregates of cytoplasmic filaments. Immunohistochemical studies demonstrated reactivity for keratin, vimentin, and smooth-muscle myosin in these structures. Because of potential diagnostic difficulties, the pathologist should be aware of this unusual form of basal cell carcinoma.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Carcinoma, Basal Cell / pathology*
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Carcinoma, Basal Cell / ultrastructure
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Female
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Humans
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Hyalin / pathology*
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Inclusion Bodies / pathology*
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Inclusion Bodies / ultrastructure
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Intermediate Filaments / pathology
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Intermediate Filaments / ultrastructure
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Keratins / analysis
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Neoplasm Recurrence, Local
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Skin Neoplasms / pathology*
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Skin Neoplasms / ultrastructure
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Staining and Labeling