Cystic, nodular and cavitary metastases to the lungs in a patient with endometrial stromal sarcoma of the uterus

Intern Med. 2014;53(9):1001-5. doi: 10.2169/internalmedicine.53.1946. Epub 2014 May 1.

Abstract

A 57-year-old woman, who had undergone hysterectomy for uterine myoma 11 years earlier presented with cystic, nodular and cavitary lesions simultaneously visible on computed tomography images of the chest. Histological examinations of both the resected lung and past "myoma" specimens demonstrated that the original uterine tumor was a low-grade endometrial stromal sarcoma (ESS) that had metastasized to the lungs. No previous reports have described the coexistence of cystic, nodular and cavitary lesions with pulmonary metastasis of ESS; however, we successfully correlated the radiologic appearance with the corresponding pathologic findings. Medroxyprogesterone acetate therapy has effectively kept the patient asymptomatic for approximately five years.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Endometrial Neoplasms / pathology*
  • Endometrial Neoplasms / surgery
  • Female
  • Humans
  • Hysterectomy
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery
  • Middle Aged
  • Pneumonectomy / methods
  • Positron-Emission Tomography
  • Sarcoma, Endometrial Stromal / diagnosis
  • Sarcoma, Endometrial Stromal / secondary*
  • Sarcoma, Endometrial Stromal / surgery
  • Thoracic Surgery, Video-Assisted
  • Tomography, X-Ray Computed