Migration of bisphenol A into canned tomatoes produced in Italy: dependence on temperature and storage conditions

Sonia Errico; Mariangela Bianco; Luigi Mita; Marina Migliaccio; Sergio Rossi; Carla Nicolucci; Ciro Menale; Marianna Portaccio; Pasquale Gallo; Damiano G Mita; Nadia Diano

doi:10.1016/j.foodchem.2014.03.085

Migration of bisphenol A into canned tomatoes produced in Italy: dependence on temperature and storage conditions

Food Chem. 2014 Oct 1:160:157-64. doi: 10.1016/j.foodchem.2014.03.085. Epub 2014 Mar 24.

Authors

Affiliations

¹ National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy.
² National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy.
³ Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy.
⁴ National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy; Department of Experimental Medicine, Università degli Studi di Messina, AOU Policlinico G. Martino, Viale Gazzi, 98122 Messina, Italy.
⁵ National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy; Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy.
⁶ Department of Experimental Medicine, Second University of Naples, Via S.M. di Costantinopoli, 16, 80138 Naples, Italy.
⁷ Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy.
⁸ National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy; Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy. Electronic address: mita@igb.cnr.it.
⁹ National Laboratory on Endocrine Disruptors, National Institute of Biostructures and Biosystems (INBB), Via P. Castellino, 111, 80131 Naples, Italy; Dipartimento di Chimica, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici (NA), Italy; Institute of Genetic and Biophysics "ABT", Via P. Castellino, 111, 80131 Naples, Italy.

PMID: 24799222
DOI: 10.1016/j.foodchem.2014.03.085

Abstract

A method based on solid-phase extraction followed by liquid chromatography, coupled to UV-visible and fluorescence spectrophotometry, has been developed for determination of bisphenol A (BPA) in canned tomatoes. The limit of quantification (LOQ) of the procedure used is 0.03 μM (0.26 μg BPA/kg tomato). For each of three different tomato based products (peeled, cherry and concentrated paste), 16 samples belonging to six commercial brands, retailed in Italian markets, were tested for migration of BPA epoxy-coating cans. All the tomato samples exhibited migration levels below 0.4 μg/kg, while samples subjected to heating process and/or can's damage by denting, exhibited a significant increase in the migration levels. In any case, no sample contained BPA exceeding the European Union limit for migration, set at 600 μg/kg of food. By comparing the results for each brand, no relevant difference in BPA concentration was found depending on the kind of tomato products.

Keywords: Bisphenol A; Canned tomatoes; HPLC; Migration; Solid-phase extraction.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzhydryl Compounds / analysis*
Chromatography, High Pressure Liquid / methods
Chromatography, Liquid
European Union
Food Contamination / analysis
Food Preservation / methods*
Food, Preserved / analysis*
Italy
Maximum Allowable Concentration
Phenols / analysis*
Solanum lycopersicum / chemistry*
Solid Phase Extraction / methods
Temperature

Substances

Benzhydryl Compounds
Phenols
bisphenol A