Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases

Chem Rev. 2014 Jul 9;114(13):6844-79. doi: 10.1021/cr400713r. Epub 2014 May 15.

Authors

Vladimir N Uversky¹, Vrushank Davé, Lilia M Iakoucheva, Prerna Malaney, Steven J Metallo, Ravi Ramesh Pathak, Andreas C Joerger

Affiliation

¹ Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute and ∥Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida , Tampa, Florida 33612, United States.

No abstract available

Publication types

Review

MeSH terms

Disease / genetics*
Humans
Intrinsically Disordered Proteins / chemistry*
Intrinsically Disordered Proteins / genetics
Mutation / physiology
Protein Unfolding*

Substances

Intrinsically Disordered Proteins

Grants and funding

P50 CA119997/CA/NCI NIH HHS/United States