Visfatin/Nampt induces telomere damage and senescence in human endothelial cells

Int J Cardiol. 2014 Aug 20;175(3):573-5. doi: 10.1016/j.ijcard.2014.05.028. Epub 2014 May 17.
No abstract available

Keywords: DNA damage; Endothelium; Nampt; Senescence; Telomere; Visfatin.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cells, Cultured
  • Cellular Senescence* / drug effects
  • Cellular Senescence* / physiology
  • Cytokines / toxicity*
  • Dose-Response Relationship, Drug
  • Endothelial Cells / drug effects
  • Endothelial Cells / metabolism
  • Endothelial Cells / pathology*
  • Humans
  • Nicotinamide Phosphoribosyltransferase / toxicity*
  • Oxidative Stress / drug effects
  • Oxidative Stress / physiology
  • Telomere / drug effects
  • Telomere / metabolism
  • Telomere / pathology*

Substances

  • Cytokines
  • Nicotinamide Phosphoribosyltransferase
  • nicotinamide phosphoribosyltransferase, human