Identification of aggregation substances of Enterococcus faecalis cells after induction by sex pheromones. An immunological and ultrastructural investigation

Arch Microbiol. 1989;151(6):486-90. doi: 10.1007/BF00454863.

Abstract

The sex pheromone system of Enterococcus faecalis is responsible for the clumping response of a plasmid carrying donor strain with a corresponding plasmid free recipient strain due to the production of sex pheromones by the recipient strain. The clumping response is mediated by a surface material (called aggregation substance) which is synthesized upon addition of sex pheromones to the cultures. Here we show that after induction a dense layer of "hairlike" structures is formed on the cell wall of the bacteria. These hairlike structures are responsible for the cell-cell contact which leads to the aggregation of cells. Formation of these structures was specific, only occurring after the addition of homologous sex pheromone.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biological Factors / analysis*
  • Biological Factors / biosynthesis
  • Biological Factors / isolation & purification
  • Blotting, Western
  • Cell Wall / analysis
  • Enterococcus faecalis / analysis
  • Enterococcus faecalis / metabolism*
  • Enterococcus faecalis / ultrastructure
  • Immunohistochemistry
  • Microscopy, Electron
  • Pheromones / metabolism*
  • Sex Attractants / metabolism*

Substances

  • Biological Factors
  • Pheromones
  • Sex Attractants