[Hepatitis B virus infection in pregnancy and the immunosuppressed patient]

Abstract

Hepatitis B virus (HBV) infection continues to be a major public health problem worldwide. Although treatment indications are well established in clinical practice guidelines, there are some risk groups, such as pregnant women and immunosuppressed patients, who require different and specific management of HBV infection. In pregnant women, treatment indication should be individualized and the risk of HBV transmission to the newborn evaluated because cases of vertical transmission continue to be reported, despite active and passive immunoprophylaxis. In patients receiving immunosuppressive therapy, HBV reactivation is associated with high morbidity and mortality, even in patients with past HBV infection, highlighting the importance of screening and the need to evaluate prophylactic therapy in some cases.

Keywords: Cancer; Chemotherapy; Cáncer; Embarazo; Hepatitis B; Immunosuppression; Inmunosupresión; Pregnancy; Quimioterapia; Rituximab; Transplantation; Trasplante.