Nine years of retained perfluoro-n-octane in the anterior chamber after retinal detachment repair with no signs of ocular toxicity

Middle East Afr J Ophthalmol. 2014 Jul-Sep;21(3):279-82. doi: 10.4103/0974-9233.134697.

Abstract

Perfluoro-n-octane (PFO) is commonly used in vitreoretinal surgery. In this case report, we present a 35-year-old patient with retained PFO up to 9 years after par plana vitrectomy. Post-operatively, PFO bubbles occupied 15% of the anterior chamber (AC). Follow-up over 9 years, consistently showed a quiet AC, normal intraocular pressure and endothelial cell counts remained stable. Until date, the patient has been under observation and there have been no ocular symptoms or side-effects. Residual PFO that inadvertently remains in the AC can be well- tolerated, without side-effects for up to 9 years.

Keywords: Anterior Chamber; Perfluoro-n-octane; Vitreo-retinal Surgery.

Publication types

  • Case Reports

MeSH terms

  • Anterior Chamber / drug effects*
  • Cell Count
  • Endotamponade*
  • Endothelium, Corneal / pathology
  • Fluorocarbons / therapeutic use*
  • Fluorocarbons / toxicity
  • Humans
  • Male
  • Retinal Detachment / surgery*
  • Visual Acuity
  • Vitreoretinal Surgery*
  • Young Adult

Substances

  • Fluorocarbons
  • perfluorooctane