Decreasing incidence of inflammatory bowel disease in eastern Canada: a population database study

BMC Gastroenterol. 2014 Aug 9:14:140. doi: 10.1186/1471-230X-14-140.

Abstract

Background: Nova Scotia has one of the highest incidences of inflammatory bowel disease (IBD) in the world. We wished to determine trends of IBD over time.

Methods: All Provincial residents have government provided health insurance and all interactions with the hospital, and physician billing systems, are captured on an administrative database. We used a validated measure to define incident cases of Crohn's (CD), ulcerative colitis (UC) and undifferentiated IBD (IBDU). Incidence rates of these diseases for the years 1996-2009 were calculated.

Results: Over the study period, 7,153 new cases of IBD were observed of which 3,046 cases were categorized as CD (42.6%), 2,960 as UC (41.4%) and 1,147 as IBDU (16.0%). Annual age standardized incidence rates were very high but have declined for CD from 27.4 to 17.7/100,000 population and for UC from 21.4 to 16.7/100,000. The decline was seen in all age groups and both genders. The decrease was not explained by a small increase in IBDU.

Conclusion: The incidence of CD and UC are decreasing in Nova Scotia. If replicated elsewhere this indicates a reversal after a long period of increasing occurrence of IBD. This has implications for both epidemiology and health planning.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Colitis, Ulcerative / epidemiology*
  • Crohn Disease / epidemiology*
  • Databases, Factual
  • Female
  • Humans
  • Incidence
  • Inflammatory Bowel Diseases / epidemiology
  • Male
  • Middle Aged
  • Nova Scotia / epidemiology
  • Young Adult