A pilot study on factors involved with work participation in the early stages of multiple sclerosis

PLoS One. 2014 Aug 25;9(8):e105673. doi: 10.1371/journal.pone.0105673. eCollection 2014.

Abstract

Background: Up to 30% of recently diagnosed MS patients lose their jobs in the first four years after diagnosis. Taking into account the personal and socio-economic importance of sustaining employment, it is of the utmost importance to examine factors involved with work participation.

Objective: To investigate differences in self-reported functioning in recently diagnosed MS patients with and without a paid job.

Methods: Self-reports of physical and cognitive functioning, depression, anxiety and fatigue were gathered from 44 relapsing-remitting MS patients diagnosed within 3 years.

Results: Patients with a paid job (57%) reported better physical functioning (p<0.001), better memory functioning (p = 0.01) and a lower physical impact of fatigue (p = 0.018) than patients without a paid job. Physical functioning was the main predictor of employment status in a logistic regression model. In those with a paid job better memory functioning (r = 0.54, p = 0.005) and a lower social impact of fatigue (r = -0.46, p = 0.029) correlated with an increased number of working hours.

Conclusion: Better physical functioning is the primary factor involved with increased work participation in early MS. Better self-reported memory functioning and less social fatigue were associated with increased working hours. These findings highlight the importance of battling these symptoms in the early stages of MS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety / complications*
  • Cognition
  • Depression / complications*
  • Employment*
  • Fatigue / complications*
  • Female
  • Humans
  • Male
  • Memory
  • Middle Aged
  • Multiple Sclerosis / complications*
  • Neuropsychological Tests
  • Pilot Projects
  • Surveys and Questionnaires
  • Work*

Grants and funding

This research was financially supported by the National Multiple Sclerosis Foundation, The Netherlands. The first author, KH, was employed by the National Multiple Sclerosis Foundation and had a role in study design, data collection and analysis, decision to publish, and preparation of the manuscript. Volunteers working for the National Multiple Sclerosis Foundation helped with data collection by sending out questionnaires.