Lichenoid mucosal reaction to rituximab

Michal Kuten-Shorrer; Ephraim P Hochberg; Sook-Bin Woo

doi:10.1634/theoncologist.2014-0169

Lichenoid mucosal reaction to rituximab

Oncologist. 2014 Oct;19(10):e12-3. doi: 10.1634/theoncologist.2014-0169. Epub 2014 Aug 28.

Authors

Michal Kuten-Shorrer¹, Ephraim P Hochberg², Sook-Bin Woo³

Affiliations

¹ Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA.
² Center for Lymphoma, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
³ Dentistry, Brigham and Women's Hospital, Boston, Massachusetts USA.

Abstract

A case of rituximab-induced oral lichenoid drug reaction in a patient with follicular non-Hodgkin lymphoma is presented. In light of the wide use of rituximab for the treatment of lymphoma and the increasing use for autoimmune diseases, awareness and recognition of this unusual side effect of treatment with rituximab is critical to allow for prompt management to reduce morbidity.

Publication types

Case Reports

MeSH terms

Adult
Anti-Inflammatory Agents / therapeutic use
Antineoplastic Agents / adverse effects*
Dexamethasone / therapeutic use
Female
Humans
Lichen Planus, Oral / etiology*
Lichen Planus, Oral / pathology
Lymphoma, Follicular / complications
Lymphoma, Follicular / drug therapy
Mouth Mucosa / pathology*
Prednisone / therapeutic use
Rituximab / adverse effects*

Substances

Anti-Inflammatory Agents
Antineoplastic Agents
Rituximab
Dexamethasone
Prednisone