Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings

MeSH terms

• Adenocarcinoma / blood
• Adenocarcinoma / complications
• Adenocarcinoma / diagnosis
• Adenocarcinoma / secondary
• Aged
• Anemia / drug therapy
• Anemia / etiology
• Anemia / therapy
• Antifibrinolytic Agents / adverse effects
• Antifibrinolytic Agents / pharmacology
• Antifibrinolytic Agents / therapeutic use*
• Antineoplastic Combined Chemotherapy Protocols / administration & dosage
• Antineoplastic Combined Chemotherapy Protocols / therapeutic use
• Blood Coagulation / drug effects*
• Carcinoma, Squamous Cell / blood
• Carcinoma, Squamous Cell / complications
• Carcinoma, Squamous Cell / secondary
• Carcinoma, Squamous Cell / surgery
• Cecal Neoplasms / blood
• Cecal Neoplasms / complications
• Cecal Neoplasms / diagnosis
• Disseminated Intravascular Coagulation / drug therapy*
• Disseminated Intravascular Coagulation / etiology
• Fatal Outcome
• Female
• Fibrinogen / pharmacology
• Fibrinogen / therapeutic use*
• Fibrinolysis
• Fluorouracil / administration & dosage
• Heart Diseases
• Hemorrhage / drug therapy*
• Hemorrhage / etiology
• Humans
• Leucovorin / administration & dosage
• Lung Neoplasms / blood
• Lung Neoplasms / secondary
• Lymphatic Metastasis / diagnosis
• Multiple Organ Failure / etiology
• Neoplasms, Multiple Primary / blood
• Neoplasms, Multiple Primary / complications
• Neoplasms, Multiple Primary / diagnosis
• Organoplatinum Compounds / administration & dosage
• Postoperative Complications / drug therapy
• Postoperative Complications / etiology
• Thrombosis
• Tranexamic Acid / adverse effects
• Tranexamic Acid / pharmacology
• Tranexamic Acid / therapeutic use*
• Vulvar Neoplasms / blood
• Vulvar Neoplasms / complications
• Vulvar Neoplasms / surgery