High positive predictive value of Xpert in a low rifampicin resistance prevalence setting

Eur Respir J. 2014 Dec;44(6):1711-3. doi: 10.1183/09031936.00115514. Epub 2014 Sep 3.

Authors

Anete Trajman¹, Betina Durovni², Valeria Saraceni³, Marcelo Cordeiro-Santos⁴, Frank Cobelens⁵, Susan van den Hof⁵

Affiliations

¹ Federal University of Rio de Janeiro, Rio de Janeiro, Brazil McGill University, Montreal, Canada atrajman@gmail.com.
² Federal University of Rio de Janeiro, Rio de Janeiro, Brazil Health Dept of Rio de Janeiro, Rio de Janeiro, Brazil.
³ Health Dept of Rio de Janeiro, Rio de Janeiro, Brazil Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.
⁴ Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil Amazonas State University, Manaus, Brazil.
⁵ Academic Medical Center and Amsterdam Institute of Global Health and Development, Amsterdam, The Netherlands KNCV Tuberculosis Foundation, The Hague, The Netherlands.

PMID: 25186257
DOI: 10.1183/09031936.00115514

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibiotics, Antitubercular / pharmacology*
Bacterial Proteins / genetics*
Brazil / epidemiology
DNA-Directed RNA Polymerases
Drug Resistance, Bacterial / genetics
Humans
Microbial Sensitivity Tests
Mycobacterium tuberculosis / drug effects
Mycobacterium tuberculosis / genetics*
Pilot Projects
Predictive Value of Tests
Prevalence
Rifampin / pharmacology*
Sensitivity and Specificity
Tuberculosis, Multidrug-Resistant / diagnosis*
Tuberculosis, Multidrug-Resistant / epidemiology
Tuberculosis, Pulmonary / diagnosis*
Tuberculosis, Pulmonary / epidemiology

Substances

Antibiotics, Antitubercular
Bacterial Proteins
rpoB protein, Mycobacterium tuberculosis
DNA-Directed RNA Polymerases
Rifampin