(N-phosphinoamidinate)cobalt-catalyzed hydroboration: alkene isomerization affords terminal selectivity

Abstract

Herein we establish the utility of a three-coordinate (N-phosphinoamidinate)cobalt(amido) pre-catalyst that is capable of effecting challenging alkene isomerization/hydroboration processes at room temperature, leading to the selective terminal addition of the boron group.

Keywords: N-phosphinoamidinate; alkene isomerization; cobalt; hydroboration; ketones.