[Ankle and foot ulcerations in a diabetic patient revealing cutaneous leishmaniasis]

J Mal Vasc. 2014 Dec;39(6):430-3. doi: 10.1016/j.jmv.2014.07.096. Epub 2014 Sep 4.
[Article in French]

Abstract

Introduction: Cutaneous leishmaniasis is a parasitic disease that typically manifests as a typical crusted ulcer called the oriental sore. Its localization on the lower limbs can be mistaken for a leg ulcer.

Case report: An 81-year-old male, native of Algeria, with type 2 diabetes, arterial hypertension and arteriopathy developed a chronic ulceration of the right ankle and foot compatible with the diagnosis of infectious diabetic foot. Non-improvement with antibiotics, local treatment and rest, and the absence of any hemodynamic arteriopathy led to skin biopsies. Polymerase chain reaction performed on biopsy samples for parasitological investigations yielded the diagnosis of cutaneous leishmaniasis due to Leishmania major. Complete healing was obtained with topical care alone, the patient having declined an etiological treatment.

Discussion: Cutaneous leishmaniasis is one of the rare infectious etiologies of chronic leg ulcers. Several therapeutic options, including abstention, can be proposed.

Keywords: Cutaneous leishmaniasis; Diabetes; Diabète; Leg ulcer; Leishmaniose cutanée; Ulcère de jambe.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Administration, Topical
  • Aged, 80 and over
  • Algeria / ethnology
  • Ankle*
  • Antiparasitic Agents / administration & dosage
  • Biopsy
  • Diabetes Complications / parasitology*
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / parasitology
  • Diabetic Foot
  • Diagnosis, Differential
  • Foot Ulcer / complications
  • Foot Ulcer / parasitology
  • France
  • Humans
  • Leg Ulcer / complications
  • Leg Ulcer / parasitology*
  • Leishmania major / genetics
  • Leishmania major / isolation & purification
  • Leishmaniasis, Cutaneous / complications*
  • Leishmaniasis, Cutaneous / drug therapy
  • Leishmaniasis, Cutaneous / parasitology
  • Male
  • Polymerase Chain Reaction
  • Skin / parasitology

Substances

  • Antiparasitic Agents