Congestive Heart Failure With Apparently Preserved Left Ventricular Systolic Function: A 10-Year Observational Study

Angiology. 2015 Sep;66(8):738-44. doi: 10.1177/0003319714551198. Epub 2014 Sep 22.

Abstract

We analyzed the clinical presentation and outcomes (from 2003 to 2013) of heart failure (HF) with apparently normal systolic function (HFPEF). Based on the echocardiographic left ventricular ejection fraction (LVEF), patients were divided into 2 groups, group 1 (<50%) and group 2 (≥50%). Of 2212 patients with HF, 20% were in group 2. Patients in group 2 were more likely to be older, females, Arabs, hypertensive, and obese (P = .001). Patients in group 1 were mostly Asians and had more troponin-T positivity (P = .001). Inhospital cardiac arrest, shock, and deaths were significantly greater in group 1. On multivariate analysis, age, ST-segment elevation myocardial infarction, lack of on-admission β-blockers, and angiotensin-converting enzyme inhibitors use were independent predictors of mortality. HFPEF is associated with less mortality compared to those who presented with reduced LVEF. On admission, use of evidence-based medications could in part predict this difference in the hospital outcome.

Keywords: Qatar; congestive heart failure; diastolic function; ejection fraction; mortality; systolic function.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Age Factors
  • Aged
  • Biomarkers / blood
  • Cardiovascular Agents / therapeutic use
  • Comorbidity
  • Female
  • Heart Failure / blood
  • Heart Failure / diagnosis
  • Heart Failure / drug therapy
  • Heart Failure / ethnology
  • Heart Failure / mortality
  • Heart Failure / physiopathology*
  • Hospital Mortality
  • Hospitalization
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Prevalence
  • Prognosis
  • Qatar / epidemiology
  • Racial Groups
  • Retrospective Studies
  • Risk Factors
  • Stroke Volume
  • Systole
  • Time Factors
  • Troponin T / blood
  • Ventricular Function, Left*

Substances

  • Biomarkers
  • Cardiovascular Agents
  • Troponin T