Aluminium phosphide is commonly used as an insecticide and can be toxic to humans at the cellular level by interfering with mitochondrial energy metabolism. We report on three cases of severe aluminium phosphide cardio-toxicity, resulting in severe decrease in both ventricular heart functions. The first case succumbed to intractable ventricular arrhythmias complicated by multi-organ failure before she died; while the other two cases required invasive hemodynamic support and eventually improved over the course of 10-14 days. We describe our experience and the challenges faced while managing one of them.
Keywords: AlP, aluminium phosphide; Aluminium phosphide toxicity; Cardiomyopathy; ECMO, extra corporeal membrane oxygenation; Extra corporal membrane oxygenation (ECMO); FFA, free fatty acid; IABP, intra-aortic balloon pump; Intra-aortic balloon pump; PH3, phosphine.