β-blockers in postoperative myocardial diastolic dysfunction: not a panacea

BMJ Case Rep. 2014 Oct 3:2014:bcr2014205124. doi: 10.1136/bcr-2014-205124.

Abstract

Successful treatment with heart rate lowering medication has been used to treat adults with chronic myocardial dysfunction of various aetiologies for a number of years. There has been recent evidence for the successful use of β-receptor blocking medication in highly selected group of infants with diastolic myocardial dysfunction. This case series demonstrates that while the use of β-receptor blockers in infants early following initial treatment of congenital left heart obstructive lesions appears promising and safe adjunct to more conventional management, the medium-term and long-term care of these patients remains as challenging as before.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use*
  • Diastole*
  • Heart Defects, Congenital / surgery*
  • Humans
  • Infant, Newborn
  • Male
  • Postoperative Complications / drug therapy*
  • Propanolamines / therapeutic use*
  • Ventricular Dysfunction, Left / drug therapy*

Substances

  • Adrenergic beta-Antagonists
  • Propanolamines
  • esmolol