Pharmacological targeting of β-catenin in normal karyotype acute myeloid leukemia blasts

Haematologica. 2015 Feb;100(2):e49-52. doi: 10.3324/haematol.2014.113118. Epub 2014 Nov 7.
No abstract available

Keywords: WNT inhibitors; WNT signaling; acute myeloid leukemia; β-catenin.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blast Crisis / drug therapy*
  • Blast Crisis / metabolism
  • Blast Crisis / pathology
  • Case-Control Studies
  • Cells, Cultured
  • Female
  • Flow Cytometry
  • Gene Expression Regulation, Leukemic / drug effects*
  • Humans
  • Karyotyping
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / metabolism
  • Leukemia, Myeloid, Acute / pathology
  • Male
  • Middle Aged
  • Small Molecule Libraries / pharmacology*
  • beta Catenin / antagonists & inhibitors*

Substances

  • Small Molecule Libraries
  • beta Catenin