Dissecting intraflagellar transport, one molecule at a time

Dev Cell. 2014 Nov 10;31(3):263-264. doi: 10.1016/j.devcel.2014.10.021. Epub 2014 Nov 10.

Abstract

Intraflagellar transport (IFT) is required for proper function of cilia, although many of the mechanistic details underlying this process are obscure. Two studies in this issue of Developmental Cell illuminate key functions of one IFT protein, IFT27, and offer clues into how IFT cargo is selected and transported.

Publication types

  • Comment

MeSH terms

  • ADP-Ribosylation Factors / metabolism*
  • Animals
  • Cilia / metabolism*
  • Signal Transduction*
  • rab GTP-Binding Proteins / metabolism*

Substances

  • intraflagellar transport 27 protein, mouse
  • ADP-Ribosylation Factors
  • Arl6 protein, mouse
  • rab GTP-Binding Proteins