Hemodynamic effects of nasal continuous positive airway pressure in preterm infants with evolving chronic lung disease, a crossover randomized trial

Friederike Beker; Sheryle R Rogerson; Stuart B Hooper; Arvind Sehgal; Peter G Davis

doi:10.1016/j.jpeds.2014.10.019

Hemodynamic effects of nasal continuous positive airway pressure in preterm infants with evolving chronic lung disease, a crossover randomized trial

J Pediatr. 2015 Feb;166(2):477-9. doi: 10.1016/j.jpeds.2014.10.019. Epub 2014 Nov 18.

Authors

Friederike Beker¹, Sheryle R Rogerson², Stuart B Hooper³, Arvind Sehgal⁴, Peter G Davis²

Affiliations

¹ The Royal Women's Hospital, Parkville, Victoria, Australia; The Mercy Hospital for Women, Heidelberg, Victoria, Australia; Monash Medical Centre, Clayton, Victoria, Australia.
² The Royal Women's Hospital, Parkville, Victoria, Australia.
³ The Ritchie Centre, Monash Institute for Medical Research, Clayton, Victoria, Australia.
⁴ Monash Medical Centre, Clayton, Victoria, Australia.

PMID: 25454930
DOI: 10.1016/j.jpeds.2014.10.019

Abstract

Previous studies suggest that high airway pressure may compromise cardiac output. We investigated the effect of 3 nasal continuous positive airway pressure levels on cardiac output in preterm infants with evolving chronic lung disease. We found that brief changes in continuous positive airway pressure did not affect cardiac output.

Publication types

Randomized Controlled Trial

MeSH terms

Cardiac Output*
Chronic Disease
Continuous Positive Airway Pressure* / methods
Cross-Over Studies
Hemodynamics
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / therapy*
Lung Diseases / physiopathology*
Lung Diseases / therapy*
Single-Blind Method

Associated data

ANZCTR/ACTRN12611001057976