Current readings: Percutaneous ablation for pulmonary metastatic disease

Semin Thorac Cardiovasc Surg. 2014 Autumn;26(3):239-48. doi: 10.1053/j.semtcvs.2014.09.003. Epub 2014 Sep 21.

Abstract

Percutaneous image-guided ablation is a technique for maintaining local control of metastatic lung lesions that may, in selected patients, confer a survival benefit over no treatment or systemic therapy alone. Although the currently accepted treatment for oligometastatic pulmonary disease is surgical resection, the existing body of literature, including the recent investigations reviewed within this article, supports a role for percutaneous ablation as an important and relatively safe therapeutic option for nonsurgical and in carefully selected surgical patients, conferring survival benefits competitive with surgical metastasectomy. Continued clinical investigations are needed to further understand the nuances of thermal technologies and applications to treat lung primary and secondary pulmonary malignancy, directly compare available therapeutic options and further define the role of percutaneous image-guided ablation in the treatment of pulmonary metastatic disease.

Keywords: cryoablation; lung ablation; lung metastasis; microwave ablation; pulmonary metastasis; radiofrequency ablation.

Publication types

  • Review

MeSH terms

  • Ablation Techniques* / adverse effects
  • Ablation Techniques* / mortality
  • Catheter Ablation
  • Cryosurgery
  • Humans
  • Lung Neoplasms / mortality
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery*
  • Metastasectomy / adverse effects
  • Metastasectomy / methods*
  • Metastasectomy / mortality
  • Microwaves
  • Risk Factors
  • Treatment Outcome