Surveillance of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae at a comprehensive cancer center in Japan, 2009-2013

Am J Infect Control. 2015 Feb;43(2):185-7. doi: 10.1016/j.ajic.2014.11.005. Epub 2014 Dec 17.

Abstract

We examined the results of surveillance of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae, which are pathogens known to cause nosocomial outbreaks, at a comprehensive cancer center in Japan over a 5-year period. We found that the admission prevalence and the incidence of ESBL-producing E coli increased during the study period, in contrast with ESBL-producing K pneumoniae, in which the parameters remained low throughout the study period.

Keywords: Escherichia coli; Extended-spectrum β-lactamase; Klebsiella pneumoniae; Surveillance.

MeSH terms

  • Cross Infection / microbiology
  • Drug Resistance, Bacterial
  • Escherichia coli / drug effects*
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology*
  • Gene Expression Regulation, Bacterial / physiology
  • Gene Expression Regulation, Enzymologic / physiology
  • Health Facilities*
  • Humans
  • Infection Control / methods
  • Japan
  • Klebsiella Infections / epidemiology
  • Klebsiella Infections / microbiology*
  • Klebsiella pneumoniae / drug effects*
  • Klebsiella pneumoniae / genetics
  • Klebsiella pneumoniae / metabolism
  • Retrospective Studies
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*

Substances

  • beta-Lactamases