Changes in preterm human milk composition with particular reference to introduction of mixed feeding

Indian Pediatr. 2014 Dec;51(12):997-9. doi: 10.1007/s13312-014-0545-2.

Abstract

Objective: To study the changes in composition of preterm milk till 6 months of age.

Methods: Milk samples from 33, 19, 7 and 12 lactating mothers (delivered <34 weeks) were analyzed on days 7, 28, 90 and 180, respectively.

Results: Triglyceride and sodium concentrations increased significantly with time and protein concentration decreased significantly over 180 days. Sodium (P=0.02) and triglyceride concentrations (P=0.06) were higher in milk samples of mothers who had introduced mixed feeding by 6 months post natal age (n=6) compared to exclusively breast-feeding mothers (n=6); but lactose and protein content was not significantly different.

Conclusions: Milk of preterm mothers has higher amount of triglycerides and sodium during introduction of mixed feeding.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Feeding*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Lactation / physiology*
  • Longitudinal Studies
  • Milk Proteins / analysis
  • Milk Proteins / metabolism
  • Milk, Human / chemistry*
  • Milk, Human / metabolism
  • Sodium / analysis
  • Sodium / metabolism
  • Triglycerides / analysis
  • Triglycerides / metabolism

Substances

  • Milk Proteins
  • Triglycerides
  • Sodium