Transcranial Doppler ultrasound in the diagnosis of brain death. Is it useful or does it delay the diagnosis?

Med Intensiva. 2015 May;39(4):244-50. doi: 10.1016/j.medin.2014.11.005. Epub 2015 Jan 9.
[Article in English, Spanish]

Abstract

Transcranial Doppler ultrasound is able to demonstrate cerebral circulatory arrest associated to brain death, being especially useful in sedated patients, or in those in which complete neurological exploration is not possible. Transcranial Doppler ulstrasound is a portable, noninvasive and high-availability technique. Among its limitations, mention must be made of the absence of acoustic windows and false-negative cases. In patients clinically diagnosed with brain death, with open skulls or with anoxia as the cause of death, cerebral blood flow can be observed by ultrasound, since cerebral circulatory arrest is not always synchronized to the clinical diagnosis. The diagnostic rate is therefore time-dependent, and this fact that must be recognized in order to avoid delays in death certification. Despite its limitations, transcranial Doppler ulstrasound helps solve common diagnostic problems, avoids the unnecessary consumption of resources, and can optimize organ harvesting for transplantation.

Keywords: Brain death; Diagnosis; Diagnóstico; Donante de órganos; Doppler transcraneal; Muerte encefálica; Organ donor; Transcranial Doppler.

MeSH terms

  • Artifacts
  • Blood Flow Velocity
  • Brain Death / diagnosis
  • Brain Death / diagnostic imaging*
  • Brain Death / legislation & jurisprudence
  • Cerebrovascular Circulation
  • Contraindications
  • Craniotomy
  • Death Certificates
  • Delayed Diagnosis
  • False Negative Reactions
  • False Positive Reactions
  • Humans
  • Hypoxia, Brain / physiopathology
  • Intracranial Hypertension / physiopathology
  • Spain
  • Time Factors
  • Tissue and Organ Procurement / legislation & jurisprudence
  • Ultrasonography, Doppler, Transcranial*