From transcriptional regulation to drugging the cancer epigenome

James E Bradner

doi:10.1186/s13073-014-0123-1

From transcriptional regulation to drugging the cancer epigenome

Genome Med. 2014 Dec 20;6(12):123. doi: 10.1186/s13073-014-0123-1. eCollection 2014.

Author

James E Bradner¹

Affiliation

¹ Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Harvard Medical School, Boston, MA 02115 USA.

Abstract

Jay Bradner discusses the opportunities and challenges for the study and therapeutic targeting of the cancer epigenome, as well as innovative approaches to drug discovery.