Childhood traumatic experiences of patients with bipolar disorder type I and type II

J Affect Disord. 2015 Apr 1:175:92-7. doi: 10.1016/j.jad.2014.12.055. Epub 2014 Dec 31.

Abstract

Background: Childhood trauma is an important environmental stressor associated with bipolar disorders (BD). It is still not clear if it is differently distributed between BD I and BD II. Therefore, the aim of this research was to investigate the distribution patterns of childhood trauma in BD I and BD II. In this perspective, we also studied the relationship between childhood trauma and suicidality.

Methods: We assessed 104 outpatients diagnosed with BD I (n=58) or BD II (n=46) according to DSM-IV-TR criteria and 103 healthy controls (HC) matched for age, sex and education level. History of childhood trauma was obtained using the Childhood Trauma Questionnaire (CTQ).

Results: All patients with BD had had more severe traumatic childhood experiences than HC. Both BD I and BD II patients differed significantly from HC for trauma summary score and emotional abuse. BD I patients differed significantly from HC for sexual abuse, and BD II differed from HC for emotional neglect. BD I and BD II did not significantly differ for any type of trauma. Suicide attempts were linked to both emotional and sexual abuse in BD I and only to emotional abuse in BD II. Emotional abuse was an independent predictor of lifetime suicide attempts in BD patients.

Limitations: The reliability of the retrospective assessment of childhood trauma experiences with the CTQ during adulthood may be influenced by uncontrolled recall bias.

Conclusions: The assessment of childhood trauma, which has great clinical importance because of its strong link with suicidality, can unveil slight differences between BD subtypes and HC.

Keywords: Bipolar disorders; Childhood trauma; Suicide.

MeSH terms

  • Adult
  • Bipolar Disorder / complications
  • Bipolar Disorder / diagnosis
  • Bipolar Disorder / psychology*
  • Case-Control Studies
  • Child
  • Child Abuse / diagnosis
  • Child Abuse / psychology*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Humans
  • Male
  • Retrospective Studies
  • Stress, Psychological / psychology*
  • Suicide
  • Suicide, Attempted / psychology
  • Surveys and Questionnaires