Childhood generalized pustular psoriasis: longtime remission with combined infliximab and methotrexate treatment

Pediatr Dermatol. 2015 Jan-Feb;32(1):e13-4. doi: 10.1111/pde.12457.

Abstract

An 8-year old boy with generalized pustular psoriasis unresponsive to several topical and systemic treatments responded dramatically with long-lasting remission to infliximab in combination with methotrexate. Combined therapy might offer a new therapeutic strategy yielding long-term remission.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal / administration & dosage
  • Antibodies, Monoclonal / therapeutic use*
  • Child
  • Dermatologic Agents / administration & dosage
  • Dermatologic Agents / therapeutic use*
  • Drug Therapy, Combination / methods*
  • Humans
  • Infliximab
  • Methotrexate / administration & dosage
  • Methotrexate / therapeutic use*
  • Psoriasis / drug therapy*
  • Remission Induction / methods
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal
  • Dermatologic Agents
  • Infliximab
  • Methotrexate