A case report of CMV lymphadenitis in an adult kidney transplant recipient

E L Lum; J M Schaenman; M DeNicola; U G Reddy; J I Shen; S T Pullarkat

doi:10.1016/j.transproceed.2014.09.105

A case report of CMV lymphadenitis in an adult kidney transplant recipient

Transplant Proc. 2015 Jan-Feb;47(1):141-5. doi: 10.1016/j.transproceed.2014.09.105.

Authors

E L Lum¹, J M Schaenman², M DeNicola³, U G Reddy⁴, J I Shen⁵, S T Pullarkat³

Affiliations

¹ UCLA David Geffen School of Medicine Department of Medicine, Division of Nephrology, Kidney Transplant, Los Angeles, Califonia, USA. Electronic address: elum@mednet.ucla.edu.
² UCLA David Geffen School of Medicine Department of Medicine, Infectious Diseases, Los Angeles, Califonia, USA.
³ UCLA David Geffen School of Medicine Department of Pathology, Los Angeles, Califonia, USA.
⁴ UCLA David Geffen School of Medicine Department of Medicine, Division of Nephrology, Kidney Transplant, Los Angeles, Califonia, USA.
⁵ UCLA Harbor Department of Medicine, Division of Nephrology, Los Angeles, Califonia, USA.

Abstract

Cytomegalovirus (CMV) infection following kidney transplantation is associated with increased morbidity and mortality. In this case report we describe a case of a 23-year-old woman with an unusual presentation of diffuse CMV lymphadenitis following kidney transplantation that did not respond to gangiclovir therapy. This case highlights the atypical presentation of CMV disease in a kidney transplant recipient, the importance of CMV hypergammaglobulin in the treatment of CMV infection post kidney transplantation, and the difficulties in transitioning care from pediatric to adult transplant programs.

Publication types

Case Reports

MeSH terms

Adult
Cytomegalovirus
Cytomegalovirus Infections* / drug therapy
Female
Humans
Kidney Transplantation / adverse effects*
Lymphadenitis / virology*

Grants and funding

KL2 TR000122/TR/NCATS NIH HHS/United States