Abstract
A multifunctional drug delivery vehicle consisting of a tubular shaped silica host, a compact superparamagnetic iron oxide nanoparticle layer and a hyaluronic acid surface coating was developed as a theranostic platform, for in vivo MR imaging and magnetically guided/cancer targeted drug delivery.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibiotics, Antineoplastic / administration & dosage
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Antibiotics, Antineoplastic / chemistry
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Cell Line, Tumor
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Cell Survival / drug effects
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Doxorubicin / administration & dosage
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Doxorubicin / chemistry
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Drug Delivery Systems*
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Drug Liberation
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Ferric Compounds / chemistry*
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Hyaluronic Acid / chemistry
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Magnetic Phenomena
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Magnetic Resonance Imaging
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Metal Nanoparticles / chemistry*
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Mice
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Nanotubes / chemistry*
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Silicon Dioxide / chemistry*
Substances
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Antibiotics, Antineoplastic
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Ferric Compounds
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ferric oxide
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Silicon Dioxide
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Doxorubicin
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Hyaluronic Acid