Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report

Int J Clin Exp Pathol. 2014 Dec 1;7(12):9032-7. eCollection 2014.

Abstract

Primary urinary bladder adenosquamous carcinoma is extremely rare and only a few cases have been reported in English literatures. Its biological behavior remains unclear. Here we reported a 60-year-old male patient with lower limb deep venous thromboses associated with primary urinary bladder adenosquamous carcinoma. A color ultrasonography showed right stock total venous thrombosis and right great saphenous vein thrombosis of lower limb. Contrast-enhanced computed tomography (CT) scan confirmed a 3.17 × 3.33 × 3.84 cm enhancing mass within the urinary bladder along the right lateral and posterior wall. Histopathological examination revealed adenosquamous carcinoma of urinary bladder, with extensive infiltration of the muscle layer. To the best of our knowledge, this is the first report of primary urinary bladder adenosquamous carcinoma complicated with deep venous thromboses in lower limb.

Keywords: Urinary bladder adenosquamous carcinoma; deep venous thromboses; hematuria; hypercoagulability.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biopsy
  • Carcinoma, Adenosquamous / chemistry
  • Carcinoma, Adenosquamous / complications*
  • Carcinoma, Adenosquamous / pathology
  • Carcinoma, Adenosquamous / surgery
  • Contrast Media
  • Cystectomy
  • Humans
  • Immunohistochemistry
  • Lower Extremity / blood supply*
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Saphenous Vein* / diagnostic imaging
  • Tomography, X-Ray Computed
  • Ultrasonography, Doppler, Color
  • Urinary Bladder Neoplasms / chemistry
  • Urinary Bladder Neoplasms / complications*
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery
  • Vena Cava Filters
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / etiology*
  • Venous Thrombosis / therapy

Substances

  • Biomarkers, Tumor
  • Contrast Media