Abstract
The N 6-methyladenosine (m6A) modification of mRNA has a crucial function in regulating pluripotency in murine stem cells: it facilitates resolution of naïve pluripotency towards differentiation.
MeSH terms
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Adenosine / analogs & derivatives
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Adenosine / metabolism
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Animals
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Cell Differentiation / genetics
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Embryonic Stem Cells / cytology
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Embryonic Stem Cells / metabolism
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Methylation
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Mice
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Phenotype
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Pluripotent Stem Cells / cytology
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Pluripotent Stem Cells / metabolism*
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RNA, Messenger / genetics*
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RNA, Messenger / metabolism
Substances
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RNA, Messenger
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N-methyladenosine
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Adenosine